GrippeCanadaV3, Main, Exploration, bibRecord, 000643

Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.

Identifieur interne : 000643 ( Main/Exploration ); précédent : 000642; suivant : 000644

Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.

Auteurs : Yoav Keynan [Canada] ; Jennifer Juno ; Adrienne Meyers ; T Blake Ball ; Anand Kumar ; Ethan Rubinstein ; Keith R. Fowke

Source :

Emerging infectious diseases [ 1080-6059 ] ; 2010.

RBID : pubmed:20875295

Descripteurs français

KwdFr :
- Adulte, Allèles, Canada (épidémiologie), Délétion de séquence, Femelle, Flambées de maladies, Grippe humaine (génétique), Grippe humaine (physiopathologie), Grippe humaine (virologie), Grippe humaine (épidémiologie), Humains, Hétérozygote, Indice de gravité médicale, Maladie grave, Mâle, Pandémies, Récepteurs CCR5 (génétique), Sous-type H1N1 du virus de la grippe A (pathogénicité).
MESH :
- génétique : Grippe humaine, Récepteurs CCR5.
- pathogénicité : Sous-type H1N1 du virus de la grippe A.
- physiopathologie : Grippe humaine.
- virologie : Grippe humaine.
- épidémiologie : Canada, Grippe humaine.
- Adulte, Allèles, Délétion de séquence, Femelle, Flambées de maladies, Humains, Hétérozygote, Indice de gravité médicale, Maladie grave, Mâle, Pandémies.
Wicri :
- geographic : Canada.

English descriptors

KwdEn :
- Adult, Alleles, Canada (epidemiology), Critical Illness, Disease Outbreaks, Female, Heterozygote, Humans, Influenza A Virus, H1N1 Subtype (pathogenicity), Influenza, Human (epidemiology), Influenza, Human (genetics), Influenza, Human (physiopathology), Influenza, Human (virology), Male, Pandemics, Receptors, CCR5 (genetics), Sequence Deletion, Severity of Illness Index.
MESH :
- chemical , genetics : Receptors, CCR5.
- geographic , epidemiology : Canada.
- epidemiology : Influenza, Human.
- genetics : Influenza, Human.
- pathogenicity : Influenza A Virus, H1N1 Subtype.
- physiopathology : Influenza, Human.
- virology : Influenza, Human.
- Adult, Alleles, Critical Illness, Disease Outbreaks, Female, Heterozygote, Humans, Male, Pandemics, Sequence Deletion, Severity of Illness Index.

Abstract

Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.

DOI: 10.3201/eid1610.100108
PubMed: 20875295

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Keynan, Yoav" sort="Keynan, Yoav" uniqKey="Keynan Y" first="Yoav" last="Keynan">Yoav Keynan</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada. keynany@yahoo.com</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba</wicri:regionArea>
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<author><name sortKey="Juno, Jennifer" sort="Juno, Jennifer" uniqKey="Juno J" first="Jennifer" last="Juno">Jennifer Juno</name>
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<author><name sortKey="Meyers, Adrienne" sort="Meyers, Adrienne" uniqKey="Meyers A" first="Adrienne" last="Meyers">Adrienne Meyers</name>
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<author><name sortKey="Ball, T Blake" sort="Ball, T Blake" uniqKey="Ball T" first="T Blake" last="Ball">T Blake Ball</name>
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<author><name sortKey="Kumar, Anand" sort="Kumar, Anand" uniqKey="Kumar A" first="Anand" last="Kumar">Anand Kumar</name>
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<author><name sortKey="Rubinstein, Ethan" sort="Rubinstein, Ethan" uniqKey="Rubinstein E" first="Ethan" last="Rubinstein">Ethan Rubinstein</name>
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<author><name sortKey="Fowke, Keith R" sort="Fowke, Keith R" uniqKey="Fowke K" first="Keith R" last="Fowke">Keith R. Fowke</name>
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<series><title level="j">Emerging infectious diseases</title>
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<term>Heterozygote</term>
<term>Humans</term>
<term>Influenza A Virus, H1N1 Subtype (pathogenicity)</term>
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<term>Maladie grave</term>
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<term>Récepteurs CCR5 (génétique)</term>
<term>Sous-type H1N1 du virus de la grippe A (pathogénicité)</term>
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<term>Flambées de maladies</term>
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<front><div type="abstract" xml:lang="en">Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.</div>
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<tree><noCountry><name sortKey="Ball, T Blake" sort="Ball, T Blake" uniqKey="Ball T" first="T Blake" last="Ball">T Blake Ball</name>
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<name sortKey="Juno, Jennifer" sort="Juno, Jennifer" uniqKey="Juno J" first="Jennifer" last="Juno">Jennifer Juno</name>
<name sortKey="Kumar, Anand" sort="Kumar, Anand" uniqKey="Kumar A" first="Anand" last="Kumar">Anand Kumar</name>
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<country name="Canada"><region name="Manitoba"><name sortKey="Keynan, Yoav" sort="Keynan, Yoav" uniqKey="Keynan Y" first="Yoav" last="Keynan">Yoav Keynan</name>
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Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.

Chemokine receptor 5 △32 allele in patients with severe pandemic (H1N1) 2009.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki